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LL-37

Also known as: Cathelicidin, hCAP-18

Evidence: PreliminaryRisk: Unknown
Administration:💉 SubQ🧴 Topical

Overview

A human antimicrobial peptide naturally produced by the body as part of the innate immune response. Research has explored its antimicrobial properties and potential role in wound healing and immune modulation.

Benefits

  • immune defense support
  • wound healing
  • skin health
  • antimicrobial properties

Potential Side Effects

  • injection site reactions
  • local irritation (topical)
  • limited human trial data

Who Should Avoid

  • pregnancy or breastfeeding
  • active infections without medical supervision
  • severe immunodeficiency or immunosuppression

Interactions & Precautions

Very limited interaction data. May affect immune responses and inflammation. Discuss all medications with clinician, especially antibiotics and immune-modulating drugs.

Dosing Information from Literature

Human clinical data is extremely limited. Preclinical research has explored a wide range of concentrations. Standardized dosing protocols have not been established.

This is descriptive information only. Always consult a licensed healthcare provider for dosing guidance.

Storage

Store unreconstituted peptide in freezer (-20°C or colder). After reconstitution, store refrigerated and use within 1-2 weeks. Sensitive to degradation.

Last reviewed: 11/3/2025