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Epitalon

Also known as: Epithalon, Epithalone, Aedg

Evidence: AnecdotalRisk: Unknown
Administration:💉 SubQ💉 IM

Overview

A synthetic tetrapeptide studied in Russia for its potential effects on the pineal gland and circadian rhythms. Research has explored its relationship with melatonin production and cellular aging markers, though human clinical data remains limited.

Benefits

  • sleep regulation
  • circadian rhythm support
  • cellular health
  • longevity research interest

Potential Side Effects

  • injection site reactions
  • drowsiness or alertness changes
  • headache
  • vivid dreams

Who Should Avoid

  • pregnancy or breastfeeding
  • active malignancy
  • severe autoimmune conditions without medical guidance
  • individuals on immunosuppressive therapy

Interactions & Precautions

Very limited interaction data available. May affect sleep-wake cycles and melatonin. Exercise caution with sleep medications, antidepressants, and immune-modulating drugs. Comprehensive medication review essential.

Dosing Information from Literature

Russian research has used protocols ranging from 5-10 mg administered over 10-20 day cycles, typically 1-2 times per year. Western clinical validation is lacking.

This is descriptive information only. Always consult a licensed healthcare provider for dosing guidance.

Storage

Store unreconstituted peptide in freezer (-20°C or colder). After reconstitution with bacteriostatic water, store refrigerated and use within 2-3 weeks.

Last reviewed: 11/3/2025