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5-Amino-1MQ

Also known as: 5-Amino-1-methylquinolinium

Evidence: PreliminaryRisk: Unknown
Administration:💊 Oral💉 SubQ

Overview

A small molecule that inhibits the enzyme NNMT (nicotinamide N-methyltransferase). Research has explored its potential effects on metabolism and energy expenditure in preclinical models.

Benefits

  • metabolic enhancement
  • weight management
  • energy expenditure
  • NAD+ optimization

Potential Side Effects

  • limited human data
  • injection site reactions (injectable)
  • digestive changes possible (oral)

Who Should Avoid

  • pregnancy or breastfeeding
  • liver disease or impaired liver function
  • metabolic disorders without clinician oversight

Interactions & Precautions

Very limited interaction data. May affect methylation and NAD+ pathways. Discuss with clinician if taking niacin supplements, NAD+ boosters, or medications affecting liver metabolism.

Dosing Information from Literature

Human clinical data is extremely limited. Animal research has explored various doses. Anecdotal protocols range widely with no established standard.

This is descriptive information only. Always consult a licensed healthcare provider for dosing guidance.

Storage

Store unreconstituted compound in cool, dry place away from light. After reconstitution (if injectable form), store refrigerated and use within 2 weeks.

Last reviewed: 11/3/2025